Purpose: To develop fast dissolving oral film to address vomiting and nausea in pediatric population.Methods: Oral films of Dimenhydrinate were prepared by solvent casting method by using hydroxypropylmethyl cellulose E5 (HPMC E5), polyethylene glycol 400 (PEG 400) and croscarmellose sodium.Solubility of dimenhydrinate was enhanced by ethanol as a
Air Quality in Southeast Brazil during COVID-19 Lockdown: A Combined Satellite and Ground-Based Data Analysis
With the current COVID-19 pandemic being spread all over the world, lockdown measures are being implemented, making air pollution levels go down in several countries.In this context, the air quality changes in the highly populated and trafficked Brazilian states of São Paulo (SP) and Rio de Janeiro (RJ) were addressed using a combination of satell
News from around the RNA world: new avenues in RNA biology, biotechnology and therapeutics from the 2022 SIBBM meeting
Since the formalization of Luggage tags the Central Dogma of molecular biology, the relevance of RNA in modulating the flow of information from DNA to proteins has been clear.More recently, the discovery of a vast set of non-coding transcripts involved in crucial aspects of cellular biology has renewed the enthusiasm of the RNA community.Moreover,
Real-Time Large-Scale Dense Mapping with Surfels
Real-time Pot Supports dense mapping systems have been developed since the birth of consumer RGB-D cameras.Currently, there are two commonly used models in dense mapping systems: truncated signed distance function (TSDF) and surfel.The state-of-the-art dense mapping systems usually work fine with small-sized regions.The generated dense surface may
Exploring the Genomic Traits of Non-toxigenic Vibrio parahaemolyticus Strains Isolated in Southern Chile
Vibrio parahaemolyticus is the leading cause of seafood-borne gastroenteritis worldwide.As reported in other countries, after the rise and fall of the pandemic strain in Chile, other post-pandemic strains have been associated with clinical cases, including strains lacking the major toxins TDH and TRH.Since the presence or absence of tdh and trh gen